Common name: Phosphatidic Acid (PA)
Synonyms: Phosphatidic acid, phosphatidic acid-enriched lecithin, Phosphatidic acids,
Mediator PA
CAS NO.: N/A
Molecular Formula: N/A
Molecular Weight: N/A
Structure:
R1 and R2 are fatty acid hydrocarbon chains
Main Specification: 50%, 70%, 80%, 98%
Test method: HPLC
Please see the typical HPLC of 50% Phosphatidic Acid (PA) as follow:
Resource: Soybean
Appearance: Brown Yellow to Light Yellow powder
Heavy Metals: NMT10ppm
Residual solvent: Conform to USP39, EP8.0
Product Main Quality Items
Specification |
50% |
70% |
80% |
Phosphatidic acid (PA)
phosphatidyl choline (PC)
phosphatidylethanolamine(PE)
Phosphatidylinositol (PI) |
>50%
<5%
<10%
<20% |
>70%
<5%
<5%
<5% |
>80%
<3%
<4%
<4% |
Peroxide Value |
<12 |
<12 |
<12 |
Moisture |
<5% |
<5% |
<3% |
Packing: 5kg, 10kg/Package
Storage: Store in cool and dry place and keep away from strong direct light and heat
Shelf Life: Two years when properly stored
Applications :
What is Phosphatidic acid?
Phosphatidic acids (PAs) are the acid forms of phosphatidates, a part of common phospholipids, major constituents of cell membranes. phosphatidic acid (PA) is a classified as a diacyl-glycerophospholipid, in which two fatty acids and a phosphate group are covalently bonded to a glycerol molecule through ester linkages. In more simple terms PA is a phospholipid that makes up a small percentage of the total phospholipid pool in the body. As such, it is a constituent of all cell membranes. Relevant to its role in bodybuilding and sports nutrition, PA acts as an intracellular lipid second messenger that regulates the important signalling protein called mammalian target of rapamycin (mTOR).
Health Benefits of Phosphatidic acid
The interest in supplementation with PA stems from its role as stimulator of the mTOR pathway, which is also the same mechanism by which leucine and protein stimulate muscle growth. To date there have been two studies exploring the effect of supplemental PA on the response to a periodised resistance training program. One study conducted by researchers from Florida found that supplementing with PA in conjunction with a 4-day per week resistance training program over 8 weeks lead to a 12.7% increase in squat strength and a 2.6% increase in lean body mass, while subjects consuming placebo showed a 9.3% improvement in squat strength and a 0.1% change in lean body mass.
The second study was conducted at the same institution but by different researchers and involved 28 subjects with an average age of 21 who also took part in an 8 week periodised resistance training program where they trained 3 times per week. Compared with placebo, subject receiving PA exhibited a significant increase in lean body mass (+2.4 kg), cross sectional area (+1.0 cm), and leg press strength (+51.9 kg) over placebo.
In summary these two studies suggest that 8 weeks of supplementation with PA is likely to be beneficial in increasing lower body strength and lean body mass.
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