Common name: Indole-3-carbinol
Synonyms: Indole-3-carbinol, 3-Indolemethanol, INDOLE-3-METHANOL (1H-Indol-3-yl)methanol
Active ingredients: Indole-3-carbinol
CAS NO.: 700-06-1
Molecular Formula: C9H9NO
Molecular Weight: 147.17
Main Specifications: 98%
Test method: HPLC
Appearance: Off-white to white powder
Heavy Metals: NMT10ppm
Residual solvent: Conform to USP39, EP8.0
Packing: 25KG/ cardboard drum
Storage: Store in cool and dry place and keep away from strong direct light and heat
Shelf Life: Two years when properly stored
broccoli, Brussels sprouts, cabbage, collards, cauliflower, kale, mustard greens, turnips, and rutabagas. Indole-3-carbinol is formed when these vegetables are cut, chewed or cooked. It can also be produced in the laboratory.
Indole-3-Carbinol balances hormone levels, improves breast health, detoxifies the intestines and liver, and supports the immune system.
Health Benefits of Indole-3-carbinol
1. Cancer Prevention
Animal studies show that diets high in cruciferous vegetables can slow cancer growth. Lab studies also suggest that I3C may improve the effectiveness of chemotherapy treatments.
In one clinical trial, I3C did clear cervical intraepithelial neoplasia (CIN) and prevent the progression of precancerous cells in people with abnormal Pap smears, a test done to screen for cervical cancer. There’s also some evidence that I3C has the opposite effect. Some animal studies have shown I3C promoting tumor growth.3
In early clinical trials, evidence suggests that I3C may reduce female breast cancer risk in some people and help eliminate precancerous cervical cells caused by the human papillomavirus (HPV).1 That said, the results of such studies have been mixed.
2. Systemic Lupus Erythematosus (SLE)
The evidence concerning i3C for the treatment of systemic lupus erythematosus is limited. In animals, the supplement reduced kidney disease and prolonged life, but no symptom improvements were noted in human females.
3. I3C in Type-2 Diabetes
I3C and its side-kick, DIM, may act as antioxidants to protect the body from damage caused by high blood glucose and insulin in type-2 diabetes (T2DM).
Laboratory research suggests it's possible that IC3 could act similarly to metformin, a T2DM drug, but DIM could even further improve carbohydrate metabolism to keep blood sugar steady and stop the liver from converting sugar into cholesterol.
This research is still in its early stages, but there's no harm in boosting your carbohydrate-heavy meals with lots of cruciferous veggies to support your blood sugar levels.