Common name: Trans-Resveratrol
CAS NO.: 501-36-0
Molecular Formula: C14-H12-O3
Molecular Weight: 228.246
Specification: 98%, 99%
Test method: HPLC
Resource: Extract from Polygonum cuspidatum
Storage: Store in cool and dry place and keep away from strong direct light and heat
Shelf Life: Two years when properly stored
What is Trans-Resveratrol ?
Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a stilbenoid, a type of natural phenol, and a phytoalexin produced naturally by several plants in response to injury or when the plant is under attack by pathogens such as bacteria or fungi. Food sources of resveratrol include the skin of grapes, blueberries, raspberries, and mulberries.
Health Benefits of Trans-Resveratrol
There are promising animal studies and some data from human clinical trials is emerging. Nowadays, Resveratrol is widely used in dietary supplements, functional beverage. The main functions of Resveratrol are as follows:
As of 2014, the results of human clinical trials with small samples sizes of the effects of resveratrol on cancer are shown. Testing of resveratrol in animal models of cancer have also shown mixed results. The strongest evidence of anticancer action of resveratrol exists for tumors it can contact directly, such as skin and gastrointestinal tract tumors. For other cancers, the evidence is certain.
Cardio protective effects
Moderate drinking of red wine is associated with a reduced risk of heart disease. This is best known as "the French paradox".
Studies suggest resveratrol in red wine may play an important role in this phenomenon. It appears to stimulate endothelial nitric oxide synthase (eNOS) activity and inhibit platelet aggregation.
Animal studies have demonstrated an antidiabetic effects of resveratrol. This compound was shown to act as agonist of PPAR gamma, nuclear receptor that is current pharmacological target for the treatment of diabetes type 2.
The oxidative stress induced by ultraviolet radiation is one of the main causes for premature skin aging. The photoprotective effects of several polyphenols known for their antioxidant properties, including resveratrol, have been investigated in silico and in topical application conditions.
Resveratrol is thought to activate an enzyme known as Sirtuin 1. Sirtuin 1 helps regulate metabolism; this may complement weight management efforts. In addition, sirtuin 1 plays an important role in the regulation of cellular life spans; it also promotes healthy insulin efficiency.
In 2003, resveratrol was found to considerably extend the lifespan of a type of yeast; later studies found that the effects were similar on worms and fruit flies. In 2006, studies investigated the impact of a high dose of this beneficial phytonutrient on a short-lived species of fish. Not only was the fish’s lifespan increased by an average of 56%, the fish maintained a higher level of activity and better learning rates for longer than the fish that were not supplemented.