Common name: Cycloastragenol
CAS NO.: 84605-18-5
Molecular Formula: C30-H50-O5
Molecular Weight: 490.72
Specification: 50%, 98%, 99%
Test method: HPLC
Resource: Astragalus membranaceus(Fisch.)Bge.
Storage: Store in cool and dry place and keep away from strong direct light and heat
Shelf Life: Two years when properly stored
What is Cycloastragenol?
Cycloastragenol is a saponin derived from Astragalus root, a plant which has been used in traditional Chinese and Eastern medicine for over 2,000 years for its apparent ability to delay the aging process. Cycloastragenol extends T cell proliferation by increasing telomerase activity. This help many cells grow their telomeres a little longer, adding more years of possible cellular reproduction that some believe will enable longer human life.
Health Benefits of Cycloastragenol
Cycloastragenol intake improved health span in normal mice.
As part of a study, the cycloastragenol was tested by UCLA scientist Rita B. Effros, The small study (using T-cells taken from 6 participants) found that it activated telomerase in cultured cells in all samples, another Astragalaus extract did not.
Toxicity testing is limited and safety for the human consumer has not been adequately demonstrated. Cycloastragenol was shown to improve biological markers associated with human health span through the lengthening of short telomeres and rescuing of old cells, although the significance of these findings in actual life expectancy is unknown. Publications in high-impact peer-reviewed journals are lacking however, and much of the online documentation supporting its use is sponsored by its manufacturers.
As disordered telomerase function is a feature of almost all cancers, there is an unknown, but theoretical risk of oncogene-mediated cancer promotion through the use of telomerase activators.