Common name: Phlorizin
CAS NO.: 60-81-1
Molecular Formula: C21-H24-O10
Molecular Weight: 436.411
Specification: 90%, 95%, 98%, 99%
Test method: HPLC
Storage: Store in cool and dry place and keep away from strong direct light and heat
Shelf Life: Two years when properly stored
What is Phlorizin?
Phlorizin, also known as phloridzin, is a compound found in several fruit trees, including apple and cherry, and the bark of pear trees. Experts have suggested that phlorizin may block glucose (sugar) absorption from the intestines and increase glucose loss in the urine.
Phlorizin and its analogs (similar chemical compounds) are being investigated for the treatment of diabetes, obesity, and stress hyperglycemia (high blood sugar levels). At this time, clinical studies investigating effects of phlorizin are lacking.
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Health Benefits of Phlorizin
Phlorizin's principal pharmacological action is to produce renal glycosuria and block intestinal glucose absorption through inhibition of the sodium–glucose symporters located in the proximal renal tubule and mucosa of the small intestine.
1. Phlorizin and Heart Health
The research done in recent years has revealed that the regular Phlorizin consumption can have various health benefits such as decreasing the risk of heart diseases and lowering the blood cholesterol level that may cause to stroke and heart problems. The special health benefits of the apple fruit can be related to the vitamins and minerals, as well as Phytonutrients such as procyanidin, epicatechin and quercetin.
2. Phlorizin and cancers
In recent years, research has revealed that Phlorizin may be influential in reducing the risk of developing several Cancers such as colon cancer, breast cancer, lung cancer, liver cancer, prostate cancer, pancreatic cancer, colorectal cancer, and ovarian cancer.
At Cornell University, some researchers after investigation of the apple skin have found numerous compounds named triterpenoids that reduce the growth of the cancer cells in breast, liver and colon. They have previously discovered that the apple extract may decrease the quantity and size of breast tumors in rats.