Common name: Naringenin
CAS NO.: 480-41-1
Molecular Formula: C15-H12-O5
Molecular Weight: 272.25
Specification: 95%, 98%, 99%
Test method: HPLC
Resource: Citrus paradisi Macfadyen
Packing: 25KG/ cardboard drum
Storage: Store in cool and dry place and keep away from strong direct light and heat
Shelf Life: Two years when properly stored
What is Naringenin?
Naringenin, a flavanone, belonging to the red, blue, purple pigments of Flavonoids (polyphenols) found predominantly in citrus fruits is considered as one of powerful antioxiant with many health benefits.
Health Benefits of Naringenin
1. Antioxidant, radical scavenging and biomolecule activity
In the affirmation of the capacity of flavonoid naringenin and its glycoside naringin in the comparison of theirs antioxidant capacities, radical scavenging and biomolecule activities found that naringenin exhibited higher antioxidant capacity and hydroxyl and superoxide radical scavenger efficiency than naringin and both flavanones were equally effective in reducing DNA damage.
2. Colon cancer
In the comparison of flavonoids and limonoids and theirs effects on colon cancer found that The ability of dietary apigenin and naringenin to reduce HMACF, lower proliferation (naringenin only) and increase apoptosis may contribute toward colon cancer prevention, according to "Apigenin and naringenin suppress colon carcinogenesis through the aberrant crypt stage in azoxymethane-treated rats"
3. Lung metastasis
In the investigation of Naringenin and its defect in lung metastasis in a breast cancer found that orally administered naringenin significantly decreased the number of metastatic tumor cells in the lung and extended the life span of tumor resected mice.
4. Anti cancers and tumors
In the study of Naringenin and its anti-cancer and tumor effects found that NGEN promotes apoptosis in rat C6 glioma model by promoting the apoptotic effect, modulation of Bcl-2/Bax ratio leads to release of Cyt C from mitochondria, thereby activation of caspase-3 and caspase-9 is mediated by enhanced expression of Cx43.