Common name: luteolin
CAS NO.: 491-70-3
Molecular Formula: C15-H10-O6
Molecular Weight: 286.24
Specification: 90%, 95%, 98%
Test method: HPLC
Packing: 25KG/ cardboard drum
Storage: Store in cool and dry place and keep away from strong direct light and heat
Shelf Life: Two years when properly stored
What is luteolin?
Luteolin is a chemical that is classified as a citrus bioflavonoid. It is a yellow crystal in pure form, which is typical for flavonoids. Luteolin has many uses as a health supplement due to its antioxidant and anti-inflammatory properties. Luteolin is produced by many plants, many of which are edible. Significant dietary sources of luteolin include citrus fruits, especially oranges. Broccoli, carrots, celery and green pepper are vegetables that also contain luteolin. Herbs with luteolin include parsley, peppermint, rosemary and oregano. Peanut hulls are one of the most important commercial sources of luteolin. These hulls are an inexpensive source since they’re a by-product of processed peanuts.
Health Benefits of luteolin
Luteolin exerts a variety of pharmacological activities and anti-oxidant properties associated with its capacity to scavenge oxygen and nitrogen species. It also shows potent anti-inflammatory activities by inhibiting nuclear factor kappa B (NFkB) signaling in immune cells.
Luteolin and brain inflammation
University of Illinois researchers report lutelin, found in celery and green peppers, can disrupt a component of the inflammatory response in the brain. Rodney Johnson of the University of Illinois at Urbana-Champaign and graduate student Saebyeol Jang found that luteolin inhibits a key pathway in the inflammatory response of microglia -- brain cells key to the body's immune defense. Microglial cells exposed to luteolin show a significantly diminished inflammatory response and there was reduced production of interleukin-6 -- used in cellular communication -- in the inflammatory pathway.
Chem Biol Interact. 2014. Luteolin enhances paclitaxel-induced apoptosis in human breast cancer MDA-MB-231 cells by blocking STAT3.
Oncol Rep. 2014. Protective effect of luteolin on cigarette smoke extract induced cellular toxicity and apoptosis in normal human bronchial epithelial cells via the Nrf2 pathway.