Common name: Emodin
CAS NO.: 518-82-1
Molecular Formula: C15-H10-O5
Molecular Weight: 270.239
Structure:
Specification: 50%, 98%
Test method: HPLC
Packing: 25KG/ cardboard drum
Storage: Store in cool and dry place and keep away from strong direct light and heat
Shelf Life: Two years when properly stored
Applications:
What is Emodin?
Emodin is a plant resin that occurs in a variety of plants including rhubarb, buckthorn and Japanese knotweed. It is a natural anthraquinone derivative that is also found in Chinese herbs like Rheum palmatum. Emodin obtained from the roots of this plant is a yellowish-orange powder and has shown a promising potential for various medical uses.
Health Benefits of Emodin
1. Anticancer Agent
Emodin inhibits the activity of tyrosine kinase, an enzyme that has been linked to formation of certain types of cancer. Vitro studies as well as those conducted on animal models have shown that emodin has the potential to inhibit cancer activity. Emodin also displays antitumor activity by targeting the blood vessels that promote blood circulation to cancer cells.
2. Anti-inflammatory Agent
In vitro and in vivo studies have shown that this plant-derived substance is anti-inflammatory. So, its use may be helpful in the treatment of inflammatory conditions including arthritis, atherosclerosis, asthma, and pancreatitis.
3. Antiviral Agent
Emodin has shown promising antiviral activity in test tube and in vivo studies. The studies observed that emodin is effective against herpes simplex viruses (HSV-1 and HSV-2). In the study, it was observed that emodin, when exposed to HSV-infested tissue culture cells. was able to suppress the proliferation of HSV-1 and HSV-2. Emodin interfered with their ability to replicate. Whereas, HSV-infected mice that were put on oral doses of emodin for a week, also showed an increase in survival rate.
4. Antibacterial
In vitro studies were also conducted to investigate the effect of emodin against cell cultures of H. pylori―the bacteria responsible for causing ulcers in the stomach. It was observed that the efficacy of emodin in suppressing the growth of H. pylori bacteria was dose-dependent. This means higher the amount of emodin, more will be the inhibition rate of H. pylori bacteria. Moreover, the DNA damage in H. pylori bacteria was found to be higher at greater doses.